Using QTL to Identify Genes and Pathways Underlying the Regulation and Production of Milk Components in Cattle

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dc.citation.issue5
dc.citation.volume13
dc.contributor.authorLopdell TJ
dc.contributor.editorPeterson S
dc.coverage.spatialSwitzerland
dc.date.accessioned2024-05-08T23:57:13Z
dc.date.available2024-05-08T23:57:13Z
dc.date.issued2023-03-02
dc.description.abstractMilk is a complex liquid, and the concentrations of many of its components are under genetic control. Many genes and pathways are known to regulate milk composition, and the purpose of this review is to highlight how the discoveries of quantitative trait loci (QTL) for milk phenotypes can elucidate these pathways. The main body of this review focuses primarily on QTL discovered in cattle (Bos taurus) as a model species for the biology of lactation, and there are occasional references to sheep genetics. The following section describes a range of techniques that can be used to help identify the causative genes underlying QTL when the underlying mechanism involves the regulation of gene expression. As genotype and phenotype databases continue to grow and diversify, new QTL will continue to be discovered, and although proving the causality of underlying genes and variants remains difficult, these new data sets will further enhance our understanding of the biology of lactation.
dc.description.confidentialfalse
dc.edition.editionMarch 2023
dc.format.pagination911-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/36899768
dc.identifier.citationLopdell TJ. (2023). Using QTL to Identify Genes and Pathways Underlying the Regulation and Production of Milk Components in Cattle.. Animals (Basel). 13. 5. (pp. 911-).
dc.identifier.doi10.3390/ani13050911
dc.identifier.eissn2076-2615
dc.identifier.elements-typejournal-article
dc.identifier.issn2076-2615
dc.identifier.number911
dc.identifier.piiani13050911
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/69528
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2076-2615/13/5/911
dc.relation.isPartOfAnimals (Basel)
dc.rights(c) 2023 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectlactation
dc.subjectlactogenesis
dc.subjectmammary biology
dc.subjectmammogenesis
dc.subjectquantitative trait loci
dc.titleUsing QTL to Identify Genes and Pathways Underlying the Regulation and Production of Milk Components in Cattle
dc.typeJournal article
pubs.elements-id480012
pubs.organisational-groupOther
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