Bone Health in Premenopausal Women with Coeliac Disease: An Observational Study.

Simple item page
dc.citation.issue14
dc.citation.volume16
dc.contributor.authorSchraders K
dc.contributor.authorCoad J
dc.contributor.authorKruger M
dc.contributor.editorIacone R
dc.coverage.spatialSwitzerland
dc.date.accessioned2024-09-09T01:40:20Z
dc.date.available2024-09-09T01:40:20Z
dc.date.issued2024-07-09
dc.description.abstractLow bone mineral density (BMD) is common in adults with coeliac disease (CD), even in individuals adhering to a gluten-free diet (GFD). Women are more likely to have low BMD and have an increased risk of osteoporosis, so women with pre-existing low BMD related to CD are at an even higher risk. BMD assessed by dual X-ray absorptiometry (DXA) and bone quality assessed through quantitative ultrasound (QUS) were investigated in 31 premenopausal women with CD consuming a GFD, and 39 matched healthy controls from the Lower North Island, New Zealand. In addition, bone metabolism and nutrient status were assessed, and four-day diet diaries were used to estimate nutrient intake. No statistically significant differences were found in BMD assessed by DXA between the two groups at the hip, lumbar spine or forearm. However, the parameters measured by the QUS were significantly lower in CD participants. Dietary data indicated significantly lower intakes of energy, dietary fibre, magnesium and phosphorus in women with CD, likely as a result of a reduced intake of wholegrain foods, and suggested that both groups had inadequate intake of calcium. No significant differences were demonstrated in biochemical parameters. BMD and bone biomarkers indicated no differences between coeliac and healthy women in New Zealand. However, these findings suggest that QUS may be more sensitive for the coeliac population, due to the disease's affect on the trabecular bone, and warrant further research.
dc.description.confidentialfalse
dc.edition.editionJuly-2 2024
dc.format.pagination2178-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/39064621
dc.identifier.citationSchraders K, Coad J, Kruger M. (2024). Bone Health in Premenopausal Women with Coeliac Disease: An Observational Study.. Nutrients. 16. 14. (pp. 2178-).
dc.identifier.doi10.3390/nu16142178
dc.identifier.eissn2072-6643
dc.identifier.elements-typejournal-article
dc.identifier.issn2072-6643
dc.identifier.number2178
dc.identifier.piinu16142178
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71433
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2072-6643/16/14/2178
dc.relation.isPartOfNutrients
dc.rights(c) 2024 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBMC
dc.subjectBMD
dc.subjectCD
dc.subjectDXA
dc.subjectGFD
dc.subjectQUS
dc.subjectbone mineral content
dc.subjectbone mineral density
dc.subjectcalcium
dc.subjectcoeliac disease
dc.subjectdual X-ray absorptiometry
dc.subjectgluten free diet
dc.subjectprotein
dc.subjectquantitative ultrasound
dc.subjectyoung women
dc.subjectHumans
dc.subjectCeliac Disease
dc.subjectFemale
dc.subjectBone Density
dc.subjectAdult
dc.subjectPremenopause
dc.subjectDiet, Gluten-Free
dc.subjectNew Zealand
dc.subjectAbsorptiometry, Photon
dc.subjectMiddle Aged
dc.subjectOsteoporosis
dc.subjectCase-Control Studies
dc.subjectNutritional Status
dc.subjectUltrasonography
dc.subjectBone and Bones
dc.subjectYoung Adult
dc.subjectBiomarkers
dc.titleBone Health in Premenopausal Women with Coeliac Disease: An Observational Study.
dc.typeJournal article
pubs.elements-id491010
pubs.organisational-groupCollege of Health
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