Comparison of Citrated Whole Blood to Native Whole Blood for Coagulation Testing Using the Viscoelastic Coagulation Monitor (VCM Vet™) in Horses.

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dc.citation.issue19
dc.citation.volume14
dc.contributor.authorVokes JR
dc.contributor.authorLovett AL
dc.contributor.authorde Kantzow MC
dc.contributor.authorRogers CW
dc.contributor.authorWilkins PA
dc.contributor.authorSykes BW
dc.contributor.editorMendoza García F
dc.coverage.spatialSwitzerland
dc.date.accessioned2024-10-21T00:18:04Z
dc.date.available2024-10-21T00:18:04Z
dc.date.issued2024-10-08
dc.description.abstractViscoelastic monitoring of horse coagulation is increasing due to its advantages over traditional coagulation testing. The use of a point-of-care viscoelastic coagulation monitor (VCM Vet™) has been validated for use in horses using native whole blood (NWB) but has not been assessed using citrated whole blood (CWB), a technique that might have advantages in practicality and precision. Blood was collected from 70 horses, tested in duplicate immediately using NWB (T0), and stored at room temperature as CWB for testing in duplicate at 1 (T1) and 4 (T4) hours after venipuncture for comparison to NWB. Of these horses, 20 were classified as clinically healthy and used to determine reference intervals for CWB at 1 and 4 h post-collection. There were clinically relevant differences in all measured viscoelastic parameters of CWB compared to NWB meaning that they cannot be used interchangeably. These differences were not consistent at T1 and T4 meaning the resting time of CWB influences the results and should be kept consistent. The use of CWB in this study also resulted in more machine errors when compared to NWB resulting in measurements that might not be interpretable.
dc.description.confidentialfalse
dc.edition.editionOctober-1 2024
dc.format.pagination2892-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/39409841
dc.identifier.citationVokes JR, Lovett AL, de Kantzow MC, Rogers CW, Wilkins PA, Sykes BW. (2024). Comparison of Citrated Whole Blood to Native Whole Blood for Coagulation Testing Using the Viscoelastic Coagulation Monitor (VCM Vet™) in Horses.. Animals (Basel). 14. 19. (pp. 2892-).
dc.identifier.doi10.3390/ani14192892
dc.identifier.eissn2076-2615
dc.identifier.elements-typejournal-article
dc.identifier.issn2076-2615
dc.identifier.number2892
dc.identifier.piiani14192892
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71777
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2076-2615/14/19/2892
dc.relation.isPartOfAnimals (Basel)
dc.rights(c) 2024 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectcoagulopathy
dc.subjectequine
dc.subjectpoint-of-care
dc.subjectviscoelastic testing
dc.titleComparison of Citrated Whole Blood to Native Whole Blood for Coagulation Testing Using the Viscoelastic Coagulation Monitor (VCM Vet™) in Horses.
dc.typeJournal article
pubs.elements-id491984
pubs.organisational-groupCollege of Health
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