Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila.

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dc.citation.volume2023
dc.contributor.authorHawley HR
dc.contributor.authorRoberts CJ
dc.contributor.authorFitzsimons HL
dc.coverage.spatialUnited States
dc.date.accessioned2024-07-23T02:38:13Z
dc.date.available2024-07-23T02:38:13Z
dc.date.issued2023-06-30
dc.description.abstractSpatial and temporal control of gene expression in Drosophila is essential in elucidating gene function. Spatial control is facilitated by the UAS/GAL4 system, and this can be coupled with additional adaptations for precise temporal control and fine tuning of gene expression levels. Here we directly compare the level of pan-neuronal transgene expression governed by nSyb-GAL4 and elav-GAL4, as well as mushroom body-specific expression alongside OK107-GAL4. We also compare the temporal modulation of gene expression in neurons with the auxin-inducible gene expression system (AGES) and temporal and regional gene expression targeting (TARGET) systems.
dc.description.confidentialfalse
dc.edition.edition2023
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37396791
dc.identifier.citationHawley HR, Roberts CJ, Fitzsimons HL. (2023). Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila.. MicroPubl Biol. 2023.
dc.identifier.doi10.17912/micropub.biology.000885
dc.identifier.eissn2578-9430
dc.identifier.elements-typejournal-article
dc.identifier.issn2578-9430
dc.identifier.number000885
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70280
dc.languageeng
dc.publisherCaltech Library
dc.publisher.urihttps://www.micropublication.org/journals/biology/micropub-biology-000885
dc.relation.isPartOfMicroPubl Biol
dc.rights(c) 2023 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleComparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila.
dc.typeJournal article
pubs.elements-id462442
pubs.organisational-groupOther
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