Effects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials.

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dc.citation.issue1
dc.citation.volume12
dc.contributor.authorMohammadparast V
dc.contributor.authorMohammadi T
dc.contributor.authorKarimi E
dc.contributor.authorMallard BL
dc.coverage.spatialUnited States
dc.date.accessioned2023-07-18T02:18:26Z
dc.date.accessioned2023-09-04T01:40:47Z
dc.date.available2023-02-13
dc.date.available2023-07-18T02:18:26Z
dc.date.available2023-09-04T01:40:47Z
dc.date.issued2023-03
dc.date.updated2023-07-16T23:59:08Z
dc.description.abstractPURPOSE OF REVIEW: The current systematic review and meta-analysis was done to evaluate the effects of selenium and probiotic co-supplementation on lipid profile and glycemia indices of the adult population using randomized controlled clinical trials (RCTs). RECENT FINDINGS: Five studies involving 282 participants with a sample size ranging from 38 to 79 were eligible to be enrolled in the current study. Co-supplementation with probiotic and selenium reduced fasting plasma glucose (WMD =  -4.02 mg/dL; 95% CI: -5.87 to -2.18; P < 0.001), insulin (WMD =  -2.50 mIU/mL; 95% CI: -3.11 to -1.90; P < 0.001), homeostatic model assessment for insulin resistance (WMD =  -0.59; 95% CI: -0.74 to -0.43; P < 0.001), quantitative insulin sensitivity check index (WMD = 0.01; 95% CI: 0.01 to 0.02; P < 0.001), total cholesterol (WMD =  -12.75 mg/dL; 95% CI: -19.44 to -6.07; P < 0.001), low-density lipoprotein cholesterol (WMD =  -7.09 mg/dL; 95% CI: -13.45 to -0.73; P = 0.029), and triglyceride (WMD =  -14.38 mg/dL; 95% CI: -23.13 to -5.62; P = 0.001). The findings of the current systematic review and meta-analysis suggested that co-supplementation with probiotics and selenium may benefit adults in terms of glycemia indices and lipid profile. However, due to the small number of included studies, further trials are needed to confirm our findings.
dc.format.extent167-180
dc.identifier10.1007/s13668-023-00448-1
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/36781602
dc.identifier.citationMohammadparast V, Mohammadi T, Karimi E, Mallard BL. (2023). Effects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials.. Curr Nutr Rep. 12. 1. (pp. 167-180).
dc.identifier.doi10.1007/s13668-023-00448-1
dc.identifier.eissn2161-3311
dc.identifier.elements-typejournal-article
dc.identifier.harvestedMassey_Dark
dc.identifier.issn2161-3311
dc.identifier.urihttp://hdl.handle.net/10179/19879
dc.languageeng
dc.relation.isPartOfCurr Nutr Rep
dc.relation.urihttps://link.springer.com/article/10.1007/s13668-023-00448-1
dc.rightsCC BY 4.0en_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/en_US
dc.subjectGlycemia indices
dc.subjectLipid profile
dc.subjectProbiotics
dc.subjectSelenium
dc.subjectAdult
dc.subjectHumans
dc.subjectCholesterol
dc.subjectDietary Supplements
dc.subjectProbiotics
dc.subjectRandomized Controlled Trials as Topic
dc.subjectSelenium
dc.subjectTriglycerides
dc.subjectLipid Metabolism
dc.titleEffects of Probiotic and Selenium Co-supplementation on Lipid Profile and Glycemia Indices: A Systematic Review and Meta-analysis of Randomized Clinical Trials.
dc.typeJournal article
pubs.elements-id459841
pubs.organisational-groupCollege of Health
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