The epidemiology of AmpC-producing Escherichia coli isolated from dairy cattle faeces on pasture-fed farms.

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dc.citation.issue10
dc.citation.volume70
dc.contributor.authorBurgess SA
dc.contributor.authorCookson AL
dc.contributor.authorBrousse L
dc.contributor.authorOrtolani E
dc.contributor.authorBenschop J
dc.contributor.authorAkhter R
dc.contributor.authorBrightwell G
dc.contributor.authorMcDougall S
dc.date.available2021
dc.date.issued2021-10
dc.descriptionRead and publish agreement 2022
dc.description.abstractIntroduction. Antibiotic use, particularly amoxicillin-clavulanic acid in dairy farming, has been associated with an increased incidence of AmpC-hyperproducing Escherichia coli.Gap statement. There is limited information on the incidence of AmpC-hyperproducing E. coli from seasonal pasture-fed dairy farms.Aim. We undertook a New Zealand wide cross-sectional study to determine the prevalence of AmpC-producing E. coli carried by dairy cattle.Methodology. Paddock faeces were sampled from twenty-six dairy farms and were processed for the selective growth of both extended-spectrum beta-lactamase (ESBL)- and AmpC-producing E. coli. Whole genome sequence analysis was carried out on 35 AmpC-producing E. coli.Results. No ESBL- or plasmid mediated AmpC-producing E. coli were detected, but seven farms were positive for chromosomal mediated AmpC-hyperproducing E. coli. These seven farms were associated with a higher usage of injectable amoxicillin antibiotics. Whole genome sequence analysis of the AmpC-producing E. coli demonstrated that the same strain (<3 SNPs difference) of E. coli ST5729 was shared between cows on a single farm. Similarly, the same strain (≤15 SNPs difference) of E. coli ST8977 was shared across two farms (separated by approximately 425 km).Conclusion. These results infer that both cow-to-cow and farm-to-farm transmission of AmpC-producing E. coli has occurred.
dc.description.publication-statusPublished
dc.identifierhttp://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000718022100020&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=c5bb3b2499afac691c2e3c1a83ef6fef
dc.identifierARTN 001447
dc.identifier.citationJOURNAL OF MEDICAL MICROBIOLOGY, 2021, 70 (10)
dc.identifier.doi10.1099/jmm.0.001447
dc.identifier.eissn1473-5644
dc.identifier.elements-id449162
dc.identifier.harvestedMassey_Dark
dc.identifier.issn0022-2615
dc.identifier.urihttps://hdl.handle.net/10179/17453
dc.relation.isPartOfJOURNAL OF MEDICAL MICROBIOLOGY
dc.subjectantimicrobial resistance
dc.subjectAmpC
dc.subjectdairy
dc.subjectEscherichia coli
dc.subject.anzsrc06 Biological Sciences
dc.subject.anzsrc07 Agricultural and Veterinary Sciences
dc.subject.anzsrc11 Medical and Health Sciences
dc.titleThe epidemiology of AmpC-producing Escherichia coli isolated from dairy cattle faeces on pasture-fed farms.
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Sciences
pubs.organisational-group/Massey University/College of Sciences/School of Veterinary Science
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