Structures of the ß-Keratin Filaments and Keratin Intermediate Filaments in the Epidermal Appendages of Birds and Reptiles (Sauropsids)

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dc.citation.issue4
dc.citation.volume12
dc.contributor.authorParry DAD
dc.coverage.spatialSwitzerland
dc.date.accessioned2023-11-28T23:39:01Z
dc.date.accessioned2024-07-25T06:34:05Z
dc.date.available2021-04-17
dc.date.available2023-11-28T23:39:01Z
dc.date.available2024-07-25T06:34:05Z
dc.date.issued2021-04
dc.description.abstractThe epidermal appendages of birds and reptiles (the sauropsids) include claws, scales, and feathers. Each has specialized physical properties that facilitate movement, thermal insulation, defence mechanisms, and/or the catching of prey. The mechanical attributes of each of these appendages originate from its fibril-matrix texture, where the two filamentous structures present, i.e., the corneous ß-proteins (CBP or ß-keratins) that form 3.4 nm diameter filaments and the α-fibrous molecules that form the 7–10 nm diameter keratin intermediate filaments (KIF), provide much of the required tensile properties. The matrix, which is composed of the terminal domains of the KIF molecules and the proteins of the epidermal differentiation complex (EDC) (and which include the terminal domains of the CBP), provides the appendages, with their ability to resist compression and torsion. Only by knowing the detailed structures of the individual components and the manner in which they interact with one another will a full understanding be gained of the physical properties of the tissues as a whole. Towards that end, newly-derived aspects of the detailed conformations of the two filamentous structures will be discussed and then placed in the context of former knowledge.
dc.format.pagination591-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/33920614
dc.identifier.citationParry DAD. (2021). Structures of the ß-Keratin Filaments and Keratin Intermediate Filaments in the Epidermal Appendages of Birds and Reptiles (Sauropsids).. Genes (Basel). 12. 4. (pp. 591-).
dc.identifier.doi10.3390/genes12040591
dc.identifier.eissn2073-4425
dc.identifier.elements-typejournal-article
dc.identifier.issn2073-4425
dc.identifier.piigenes12040591
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70440
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.relation.isPartOfGenes (Basel)
dc.rights(c) 2021 The Author/s
dc.rightsCC BY
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectX-ray fiber diffraction
dc.subjectcorneous ß-proteins
dc.subjectkeratin intermediate filaments
dc.subjectAnimals
dc.subjectBiological Evolution
dc.subjectBirds
dc.subjectEpidermis
dc.subjectIntermediate Filaments
dc.subjectProtein Domains
dc.subjectReptiles
dc.subjectbeta-Keratins
dc.titleStructures of the ß-Keratin Filaments and Keratin Intermediate Filaments in the Epidermal Appendages of Birds and Reptiles (Sauropsids)
dc.typeJournal article
pubs.elements-id444906
pubs.organisational-groupOther
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