Assessment of Various Food Proteins as Structural Materials for Delivery of Hydrophobic Polyphenols Using a Novel Co-Precipitation Method

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dc.citation.issue8
dc.citation.volume28
dc.contributor.authorRashidinejad A
dc.contributor.authorNieuwkoop M
dc.contributor.authorSingh H
dc.contributor.authorJameson GB
dc.contributor.editorPapetti A
dc.coverage.spatialSwitzerland
dc.date.accessioned2024-05-20T21:41:06Z
dc.date.available2024-05-20T21:41:06Z
dc.date.issued2023-04-19
dc.description.abstractIn this study, sodium caseinate (NaCas), soy protein isolate (SPI), and whey protein isolate (WPI) were used as structural materials for the delivery of rutin, naringenin, curcumin, hesperidin, and catechin. For each polyphenol, the protein solution was brought to alkaline pH, and then the polyphenol and trehalose (as a cryo-protectant) were added. The mixtures were later acidified, and the co-precipitated products were lyophilized. Regardless of the type of protein used, the co-precipitation method exhibited relatively high entrapment efficiency and loading capacity for all five polyphenols. Several structural changes were seen in the scanning electron micrographs of all polyphenol-protein co-precipitates. This included a significant decrease in the crystallinity of the polyphenols, which was confirmed by X-ray diffraction analysis, where amorphous structures of rutin, naringenin, curcumin, hesperidin, and catechin were revealed after the treatment. Both the dispersibility and solubility of the lyophilized powders in water were improved dramatically (in some cases, >10-fold) after the treatment, with further improvements observed in these properties for the powders containing trehalose. Depending on the chemical structure and hydrophobicity of the tested polyphenols, there were differences observed in the degree and extent of the effect of the protein on different properties of the polyphenols. Overall, the findings of this study demonstrated that NaCas, WPI, and SPI can be used for the development of an efficient delivery system for hydrophobic polyphenols, which in turn can be incorporated into various functional foods or used as supplements in the nutraceutical industry.
dc.description.confidentialfalse
dc.edition.editionApril 2023
dc.format.pagination3573-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37110808
dc.identifier.citationRashidinejad A, Nieuwkoop M, Singh H, Jameson GB. (2023). Assessment of Various Food Proteins as Structural Materials for Delivery of Hydrophobic Polyphenols Using a Novel Co-Precipitation Method.. Molecules. 28. 8. (pp. 3573-).
dc.identifier.doi10.3390/molecules28083573
dc.identifier.eissn1420-3049
dc.identifier.elements-typejournal-article
dc.identifier.issn1420-3049
dc.identifier.number3573
dc.identifier.piimolecules28083573
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/69621
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/1420-3049/28/8/3573
dc.relation.isPartOfMolecules
dc.rights(c) 2023 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectbioactive delivery
dc.subjectfood-grade proteins
dc.subjectfunctional foods
dc.subjecthydrophobic polyphenols
dc.subjectpolyphenols
dc.subjectpolyphenol–protein co-precipitation
dc.subjectPolyphenols
dc.subjectCatechin
dc.subjectCurcumin
dc.subjectHesperidin
dc.subjectPowders
dc.subjectTrehalose
dc.subjectHydrophobic and Hydrophilic Interactions
dc.subjectSoybean Proteins
dc.subjectRutin
dc.subjectWhey Proteins
dc.titleAssessment of Various Food Proteins as Structural Materials for Delivery of Hydrophobic Polyphenols Using a Novel Co-Precipitation Method
dc.typeJournal article
pubs.elements-id461182
pubs.organisational-groupOther
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