Therapy of Subclinical Mastitis during Lactation

Simple item page
dc.citation.issue2
dc.citation.volume11
dc.contributor.authorMcDougall S
dc.contributor.authorClausen LM
dc.contributor.authorHussein HM
dc.contributor.authorCompton CWR
dc.contributor.editorKrömker V
dc.coverage.spatialSwitzerland
dc.date.accessioned2024-01-18T19:22:57Z
dc.date.accessioned2024-07-25T06:51:30Z
dc.date.available2022-02-07
dc.date.available2024-01-18T19:22:57Z
dc.date.available2024-07-25T06:51:30Z
dc.date.issued2022-02-07
dc.description.abstractThis study tested the hypothesis that increasing the duration and/or frequency of antimicrobial treatment of subclinical mastitis would result in a higher bacteriological cure rate. Glands with a positive California mastitis test (CMT) from cows with an elevated somatic cell count (>500,000 cells/mL) that had an intramammary infection were randomly assigned at cow level to no treatment (Control; n = 80 glands), intramammary infusion of 200 mg cloxacillin sodium on three occasions at 48 h intervals (3 × 48 h; n = 273 glands), five occasions at 24 h intervals (5 × 24 h; n = 279 glands), or on five occasions at 48 h intervals (5 × 48 h; n = 72 glands). Glands were resampled at 21 (±3) and 28 (±3) days after initiation of treatment. The gland-level cure rate for any pathogen was 5/80 (6.2%), 139/173 (49.8%), 172/297 (61.6%) and 58/72 (80.6%) for Control, 3 × 48 h, 5 × 24 h and 5 × 48 h, respectively. The cure rate for major pathogens (defined as Staphylococcus aureus or Streptococcus spp.) was 4/52 (7.7%), 84/197 (42.6%), 96/183 (52.5%) and 36/48 (75%) for Control, 3 × 48 h, 5 × 24 h and 5 × 48 h, respectively. We conclude that treatment was superior to no treatment, and bacteriological cure rate was higher with the 5 × 24 h protocol than for the 3 × 48 h protocol and was higher with the 5 × 48 h than the 5 × 24 h protocol.
dc.description.confidentialfalse
dc.edition.editionFebruary 2022
dc.format.pagination209-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/35203812
dc.identifier.citationMcDougall S, Clausen LM, Hussein HM, Compton CWR. (2022). Therapy of Subclinical Mastitis during Lactation.. Antibiotics (Basel). 11. 2. (pp. 209-).
dc.identifier.doi10.3390/antibiotics11020209
dc.identifier.eissn2079-6382
dc.identifier.elements-typejournal-article
dc.identifier.issn2079-6382
dc.identifier.number209
dc.identifier.piiantibiotics11020209
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71035
dc.languageeng
dc.publisherMDPI (Basel, Switzerland)
dc.publisher.urihttps://www.mdpi.com/2079-6382/11/2/209
dc.relation.isPartOfAntibiotics (Basel)
dc.rights(c) 2022 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectStaphylococcus aureus
dc.subjectStreptococcus uberis
dc.subjectcloxacillin
dc.subjectduration
dc.subjectfrequency
dc.subjectmastitis
dc.subjectsubclinical
dc.subjecttherapy
dc.titleTherapy of Subclinical Mastitis during Lactation
dc.typeJournal article
pubs.elements-id451267
pubs.organisational-groupOther
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