Dientamoeba fragilis associated with microbiome diversity changes in acute gastroenteritis patients.

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dc.citation.volume97
dc.contributor.authorMuhsin-Sharafaldine M-R
dc.contributor.authorAbdel Rahman L
dc.contributor.authorSuwanarusk R
dc.contributor.authorGrant J
dc.contributor.authorParslow G
dc.contributor.authorFrench N
dc.contributor.authorTan KSW
dc.contributor.authorRussell B
dc.contributor.authorMorgan XC
dc.contributor.authorUssher JE
dc.coverage.spatialNetherlands
dc.date.accessioned2024-08-07T21:25:28Z
dc.date.available2024-08-07T21:25:28Z
dc.date.issued2023-12-01
dc.description.abstractThis study examined the correlation between intestinal protozoans and the bacterial microbiome in faecal samples collected from 463 patients in New Zealand who were diagnosed with gastroenteritis. In comparison to traditional microscopic diagnosis methods, Multiplexed-tandem PCR proved to be more effective in detecting intestinal parasites. Among the identified protozoans, Blastocystis sp. and Dientamoeba fragilis were the most prevalent. Notably, D. fragilis was significantly associated with an increase in the alpha-diversity of host prokaryotic microbes. Although the exact role of Blastocystis sp. and D. fragilis as the primary cause of gastroenteritis remains debatable, our data indicates a substantial correlation between these protozoans and the prokaryote microbiome of their hosts, particularly when compared to other protists or patients with gastroenteritis but no detectable parasitic cause. These findings underscore the significance of comprehending the contributions of intestinal protozoans, specifically D. fragilis, to the development of gastroenteritis and their potential implications for disease management.
dc.description.confidentialfalse
dc.edition.editionDecember 2023
dc.format.pagination102788-
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37482266
dc.identifier.citationMuhsin-Sharafaldine M-R, Abdel Rahman L, Suwanarusk R, Grant J, Parslow G, French N, Tan KSW, Russell B, Morgan XC, Ussher JE. (2023). Dientamoeba fragilis associated with microbiome diversity changes in acute gastroenteritis patients.. Parasitol Int. 97. (pp. 102788-).
dc.identifier.doi10.1016/j.parint.2023.102788
dc.identifier.eissn1873-0329
dc.identifier.elements-typejournal-article
dc.identifier.issn1383-5769
dc.identifier.number102788
dc.identifier.piiS1383-5769(23)00065-X
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71229
dc.languageeng
dc.publisherElsevier B.V.
dc.publisher.urihttps://www.sciencedirect.com/science/article/pii/S138357692300065X?
dc.relation.isPartOfParasitol Int
dc.rights(c) 2023 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBlastocystis hominis
dc.subjectCryptosporidium spp.
dc.subjectDientamoeba fragilis
dc.subjectGastroenteritis
dc.subjectGiardia spp.
dc.subjectMicrobiome
dc.subjectAnimals
dc.subjectHumans
dc.subjectDientamoeba
dc.subjectIntestinal Diseases, Parasitic
dc.subjectBlastocystis
dc.subjectGastroenteritis
dc.subjectParasites
dc.subjectFeces
dc.titleDientamoeba fragilis associated with microbiome diversity changes in acute gastroenteritis patients.
dc.typeJournal article
pubs.elements-id478981
pubs.organisational-groupOther
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