A genome-wide scan of positive selection signature using Ovine Infinium® HD SNP BeadChip in two Romney lines, selected for resistance or resilience to nematodes
dc.contributor.author | Yan J | |
dc.contributor.author | Dukkipati VSR | |
dc.contributor.author | Blair HT | |
dc.contributor.author | Biggs PJ | |
dc.contributor.author | Hamie JC | |
dc.contributor.author | Greer A | |
dc.coverage.spatial | Townsville, QLD, Australia | |
dc.date.available | 3/07/2017 | |
dc.date.finish-date | 5/07/2017 | |
dc.date.issued | 3/07/2017 | |
dc.date.start-date | 2/07/2017 | |
dc.description.abstract | A study was undertaken to identify selection signatures associated with resistance to gastrointestinal nematodiasis in sheep. Ninety-three Romney sheep from two selection lines (resistant or resilient) were genotyped using the Ovine Infinium® HD SNP BeadChip, and extended haplotype homozygosity (EHH) and site-specific extended haplotype homozygosity (EHHS) analyses were undertaken. In total, 224 SNPs (147 in EHH and 77 in EHHS) were found to be significant (p <0.0001). Preliminary exploration of 10 SNPs found them to be located within two previously identified QTLs, namely LATRICH_2 and FECGEN, which were associated with nematode larval count and faecal egg count, respectively. | |
dc.identifier.citation | 2017 | |
dc.identifier.elements-id | 375680 | |
dc.identifier.harvested | Massey_Dark | |
dc.identifier.uri | https://hdl.handle.net/10179/11864 | |
dc.rights | The Author(s) | |
dc.source | 22nd Conference of the Association for the Advancement of Animal Breeding and Genetics | |
dc.title | A genome-wide scan of positive selection signature using Ovine Infinium® HD SNP BeadChip in two Romney lines, selected for resistance or resilience to nematodes | |
dc.type | conference | |
pubs.notes | Not known | |
pubs.organisational-group | /Massey University | |
pubs.organisational-group | /Massey University/College of Sciences | |
pubs.organisational-group | /Massey University/College of Sciences/School of Agriculture & Environment |
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