Undetectable vitamin D3 in equine skin irradiated with ultraviolet light

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dc.citation.issue3
dc.citation.volume33
dc.contributor.authorAzarpeykan S
dc.contributor.authorGee EK
dc.contributor.authorThompson KG
dc.contributor.authorDittmer KE
dc.coverage.spatialJapan
dc.date.accessioned2024-01-19T02:09:15Z
dc.date.accessioned2024-07-25T06:39:15Z
dc.date.available2022-09-21
dc.date.available2024-01-19T02:09:15Z
dc.date.available2024-07-25T06:39:15Z
dc.date.issued2022-09-29
dc.description.abstractVitamin D requirements for most animals are expected to be fulfilled through daily exposure of the skin to solar ultraviolet B radiation. The synthesis of vitamin D3 in skin depends on different factors including melanin pigmentation, the amount of UVB radiation reaching the skin, type of clothing/hair coat, latitude and altitude, season, and time of day. Alternatively vitamin D2 may be obtained from UVB irradiated pasture species. Recent studies have shown that in unsupplemented grazing horses 25-hydroxyvitamin D2 is the predominant form of vitamin D in plasma, and that 25OHD3 is undetectable suggesting horses may rely on diet to obtain vitamin D. In order to mimic the natural environment of skin to sunlight exposure, five equine and two ovine devitalized skin samples were irradiated with 5 J/cm2 of UVB light followed by measurement of 7-dehydrocholesterol (7-DHC) and vitamin D3 concentrations using reverse-phase high pressure liquid chromatography (HPLC). HPLC revealed the presence of 7-DHC in the skin of both horses and sheep. Vitamin D3 was undetectable in both ovine and equine skin prior to irradiation, but after irradiation with UVB light, ovine skin showed an increase in vitamin D3 concentration (mean 0.16 ± 0.07 µg/g), whereas vitamin D3 was undetectable in equine skin. These results provide additional evidence that horses make negligible quantities of vitamin D3 in their skin after exposure to UVB light and may therefore rely on their diet as a primary source of vitamin D.
dc.description.confidentialfalse
dc.format.pagination45-49
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/36196139
dc.identifier.citationAzarpeykan S, Gee EK, Thompson KG, Dittmer KE. (2022). Undetectable vitamin D3 in equine skin irradiated with ultraviolet light.. J Equine Sci. 33. 3. (pp. 45-49).
dc.identifier.doi10.1294/jes.33.45
dc.identifier.eissn1347-7501
dc.identifier.elements-typejournal-article
dc.identifier.issn1340-3516
dc.identifier.pii2204
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/70621
dc.languageeng
dc.publisherJapanese Society of Equine Science
dc.publisher.urihttps://www.jstage.jst.go.jp/article/jes/33/3/33_2204/_article
dc.relation.isPartOfJ Equine Sci
dc.rights©2022 Japanese Society of Equine Science
dc.rightsCC BY-NC-ND 4.0
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subject7-dehydrocholesterol
dc.subjectcholecalciferol
dc.subjecthorse
dc.subjectskin
dc.subjectultraviolet light
dc.titleUndetectable vitamin D3 in equine skin irradiated with ultraviolet light
dc.typeJournal article
pubs.elements-id457149
pubs.organisational-groupOther
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