Infant Complementary Feeding of Prebiotics for the Microbiome and Immunity
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Date
2019-02-09
Open Access Location
Journal Title
Journal ISSN
Volume Title
Publisher
MDPI (Basel, Switzerland)
Rights
(c) 2019 The Author/s
CC BY 4.0
CC BY 4.0
Abstract
Complementary feeding transitions infants from a milk-based diet to solid foods, providing essential nutrients to the infant and the developing gut microbiome while influencing immune development. Some of the earliest microbial colonisers readily ferment select oligosaccharides, influencing the ongoing establishment of the microbiome. Non-digestible oligosaccharides in prebiotic-supplemented formula and human milk oligosaccharides promote commensal immune-modulating bacteria such as Bifidobacterium, which decrease in abundance during weaning. Incorporating complex, bifidogenic, non-digestible carbohydrates during the transition to solid foods may present an opportunity to feed commensal bacteria and promote balanced concentrations of beneficial short chain fatty acid concentrations and vitamins that support gut barrier maturation and immunity throughout the complementary feeding window.
Description
Keywords
gut barrier, metabolites, non‐digestible carbohydrates, oligosaccharides, tolerance, weaning, Breast Feeding, Gastrointestinal Microbiome, Humans, Infant, Infant Formula, Infant Nutritional Physiological Phenomena, Milk, Human, Oligosaccharides, Prebiotics, Weaning
Citation
McKeen S, Young W, Mullaney J, Fraser K, McNabb WC, Roy NC. (2019). Infant Complementary Feeding of Prebiotics for theMicrobiome and Immunity.. Nutrients. 11. 2. (pp. E364-).