Occupation and risk of upper aerodigestive tract cancer: The ARCAGE study

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dc.citation.issue10
dc.citation.volume130
dc.contributor.authorRichiardi L
dc.contributor.authorCorbin M
dc.contributor.authorMarron M
dc.contributor.authorAhrens W
dc.contributor.authorPohlabeln H
dc.contributor.authorLagiou P
dc.contributor.authorMinaki P
dc.contributor.authorAgudo A
dc.contributor.authorCastellsague X
dc.contributor.authorSlamova A
dc.contributor.authorSchejbalova M
dc.contributor.authorKjaerheim K
dc.contributor.authorBarzan L
dc.contributor.authorTalamini R
dc.contributor.authorMacFarlane GJ
dc.contributor.authorMacFarlane TV
dc.contributor.authorCanova C
dc.contributor.authorSimonato L
dc.contributor.authorConway DI
dc.contributor.authorMcKinney PA
dc.contributor.authorSneddon L
dc.contributor.authorThomson P
dc.contributor.authorZnaor A
dc.contributor.authorHealy CM
dc.contributor.authorMcCartan BE
dc.contributor.authorBenhamou S
dc.contributor.authorBouchardy C
dc.contributor.authorHashibe M
dc.contributor.authorBrennan P
dc.contributor.authorMerletti F
dc.coverage.spatialUnited States
dc.date.available2012-05-15
dc.date.available2011-05-13
dc.date.issued15/05/2012
dc.description.abstractWe investigated the association between occupational history and upper aerodigestive tract (UADT) cancer risk in the ARCAGE European case-control study. The study included 1,851 patients with incident cancer of the oral cavity, oropharynx, hypopharynx, larynx or esophagus and 1,949 controls. We estimated odds ratios (OR) and 95% confidence intervals (CI) for ever employment in 283 occupations and 172 industries, adjusting for smoking and alcohol. Men (1,457 cases) and women (394 cases) were analyzed separately and we incorporated a semi-Bayes adjustment approach for multiple comparisons. Among men, we found increased risks for occupational categories previously reported to be associated with at least one type of UADT cancer, including painters (OR = 1.74, 95% CI: 1.01-3.00), bricklayers (1.58, 1.05-2.37), workers employed in the erection of roofs and frames (2.62, 1.08-6.36), reinforced concreters (3.46, 1.11-10.8), dockers (2.91, 1.05-8.05) and workers employed in the construction of roads (3.03, 1.23-7.46), general construction of buildings (1.44, 1.12-1.85) and cargo handling (2.60, 1.17-5.75). With the exception of the first three categories, risks both increased when restricting to long duration of employment and remained elevated after semi-Bayes adjustment. Increased risks were also found for loggers (3.56, 1.20-10.5) and cattle and dairy farming (3.60, 1.15-11.2). Among women, there was no clear evidence of increased risks of UADT cancer in association with occupations or industrial activities. This study provides evidence of an association between some occupational categories and UADT cancer risk among men. The most consistent findings, also supported by previous studies, were obtained for specific workers employed in the construction industry. © 2011 UICC.
dc.description.publication-statusPublished
dc.format.extent2397 - 2406
dc.identifierhttps://www.ncbi.nlm.nih.gov/pubmed/21671472
dc.identifier.citationInt J Cancer, 2012, 130 (10), pp. 2397 - 2406
dc.identifier.doi10.1002/ijc.26237
dc.identifier.eissn1097-0215
dc.identifier.elements-id380020
dc.identifier.harvestedMassey_Dark
dc.identifier.urihttps://hdl.handle.net/10179/13257
dc.languageeng
dc.publisherWiley Online
dc.relation.isPartOfInt J Cancer
dc.relation.urihttps://onlinelibrary.wiley.com/doi/abs/10.1002/ijc.26237
dc.subjectAdult
dc.subjectAged
dc.subjectCase-Control Studies
dc.subjectConstruction Industry
dc.subjectEsophageal Neoplasms
dc.subjectEurope
dc.subjectFemale
dc.subjectHumans
dc.subjectLaryngeal Neoplasms
dc.subjectMale
dc.subjectMiddle Aged
dc.subjectMouth Neoplasms
dc.subjectNeoplasms
dc.subjectOccupations
dc.subjectPharyngeal Neoplasms
dc.subjectRisk
dc.subjectRisk Factors
dc.subject.anzsrc1112 Oncology and Carcinogenesis
dc.titleOccupation and risk of upper aerodigestive tract cancer: The ARCAGE study
dc.typeJournal article
pubs.notesNot known
pubs.organisational-group/Massey University
pubs.organisational-group/Massey University/College of Health
pubs.organisational-group/Massey University/College of Health/Research Centre for Hauora and Health
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