Smart capsules for sensing and sampling the gut: status, challenges and prospects

Simple item page
dc.citation.issue1
dc.citation.volume73
dc.contributor.authorRehan M
dc.contributor.authorAl-Bahadly I
dc.contributor.authorThomas DG
dc.contributor.authorYoung W
dc.contributor.authorCheng LK
dc.contributor.authorAvci E
dc.coverage.spatialEngland
dc.date.accessioned2024-10-07T20:30:26Z
dc.date.available2024-10-07T20:30:26Z
dc.date.issued2024-01
dc.description.abstractSmart capsules are developing at a tremendous pace with a promise to become effective clinical tools for the diagnosis and monitoring of gut health. This field emerged in the early 2000s with a successful translation of an endoscopic capsule from laboratory prototype to a commercially viable clinical device. Recently, this field has accelerated and expanded into various domains beyond imaging, including the measurement of gut physiological parameters such as temperature, pH, pressure and gas sensing, and the development of sampling devices for better insight into gut health. In this review, the status of smart capsules for sensing gut parameters is presented to provide a broad picture of these state-of-the-art devices while focusing on the technical and clinical challenges the devices need to overcome to realise their value in clinical settings. Smart capsules are developed to perform sensing operations throughout the length of the gut to better understand the body's response under various conditions. Furthermore, the prospects of such sensing devices are discussed that might help readers, especially health practitioners, to adapt to this inevitable transformation in healthcare. As a compliment to gut sensing smart capsules, significant amount of effort has been put into the development of robotic capsules to collect tissue biopsy and gut microbiota samples to perform in-depth analysis after capsule retrieval which will be a game changer for gut health diagnosis, and this advancement is also covered in this review. The expansion of smart capsules to robotic capsules for gut microbiota collection has opened new avenues for research with a great promise to revolutionise human health diagnosis, monitoring and intervention.
dc.description.confidentialfalse
dc.edition.editionJanuary 2024
dc.format.pagination186-202
dc.identifier.author-urlhttps://www.ncbi.nlm.nih.gov/pubmed/37734912
dc.identifier.citationRehan M, Al-Bahadly I, Thomas DG, Young W, Cheng LK, Avci E. (2023). Smart capsules for sensing and sampling the gut: status, challenges and prospects.. Gut. 73. 1. (pp. 186-202).
dc.identifier.doi10.1136/gutjnl-2023-329614
dc.identifier.eissn1468-3288
dc.identifier.elements-typejournal-article
dc.identifier.issn0017-5749
dc.identifier.piigutjnl-2023-329614
dc.identifier.urihttps://mro.massey.ac.nz/handle/10179/71612
dc.languageeng
dc.publisherBMJ Publishing Group Ltd on behalf of the British Society of Gastroenterology
dc.publisher.urihttps://gut.bmj.com/content/73/1/186
dc.relation.isPartOfGut
dc.rights(c) 2024 The Author/s
dc.rightsCC BY 4.0
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectcolonic microflora
dc.subjectenteric bacterial microflora
dc.subjectgastrointesinal endoscopy
dc.subjectintestinal bacteria
dc.subjectsmall intestine
dc.subjectHumans
dc.subjectBiopsy
dc.subjectRobotics
dc.subjectCapsule Endoscopy
dc.subjectGastrointestinal Tract
dc.subjectGastrointestinal Microbiome
dc.titleSmart capsules for sensing and sampling the gut: status, challenges and prospects
dc.typeJournal article
pubs.elements-id480741
pubs.organisational-groupOther
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