Browsing by Author "Zhang L"

Now showing 1 - 4 of 4
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    Astragalosides Supplementation Enhances Intrinsic Muscle Repair Capacity Following Eccentric Exercise-Induced Injury
    (MDPI (Basel, Switzerland), 2022-10) Yeh T-S; Lei T-H; Barnes MJ; Zhang L
    Astragalosides have been shown to enhance endurance exercise capacity in vivo and promote muscular hypertrophy in vitro. However, it remains unknown whether astragalosides supplementation can alter inflammatory response and enhance muscle recovery after damage in humans. We therefore aimed to evaluate the effect of astragalosides supplementation on muscle's intrinsic capacity to regenerate and repair itself after exercise-induced damage. Using a randomized double-blind placebo-controlled cross-over design, eleven male participants underwent 7 days of astragalosides supplementation (in total containing 4 mg of astragalosides per day) or a placebo control, following an eccentric exercise protocol. Serum blood samples and variables related to muscle function were collected prior to and immediately following the muscle damage protocol and also at 2 h, and 1, 2, 3, 5, and 7 days of the recovery period, to assess the pro-inflammatory cytokine response, the secretion of muscle regenerative factors, and muscular strength. Astragalosides supplementation reduced biomarkers of skeletal muscle damage (serum CK, LDH, and Mb), when compared to the placebo, at 1, 2, and 3 days following the muscle damage protocol. Astragalosides supplementation suppressed the secretion of IL-6 and TNF-α, whilst increasing the release of IGF-1 during the initial stages of muscle recovery. Furthermore, following astragaloside supplementation, muscular strength returned to baseline 2 days earlier than the placebo. Astragalosides supplementation shortens the duration of inflammation, enhances the regeneration process and restores muscle strength following eccentric exercise-induced injury.
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    Functional response and prey stage preference of Neoseiulus barkeri on Trasonemus confuses
    (Systematic and Applied Acarology Society London, 23/11/2018) Li L; Jiao R; Lichen Y; He XZ; He L; Xu C; Zhang L; Liu J
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    Test flakiness’ causes, detection, impact and responses: A multivocal review
    (Elsevier Inc, 2023-12) Tahir A; Rasheed S; Dietrich J; Hashemi N; Zhang L
    Flaky tests (tests with non-deterministic outcomes) pose a major challenge for software testing. They are known to cause significant issues, such as reducing the effectiveness and efficiency of testing and delaying software releases. In recent years, there has been an increased interest in flaky tests, with research focusing on different aspects of flakiness, such as identifying causes, detection methods and mitigation strategies. Test flakiness has also become a key discussion point for practitioners (in blog posts, technical magazines, etc.) as the impact of flaky tests is felt across the industry. This paper presents a multivocal review that investigates how flaky tests, as a topic, have been addressed in both research and practice. Out of 560 articles we reviewed, we identified and analysed a total of 200 articles that are focused on flaky tests (composed of 109 academic and 91 grey literature articles/posts) and structured the body of relevant research and knowledge using four different dimensions: causes, detection, impact and responses. For each of those dimensions, we provide categorization and classify existing research, discussions, methods and tools With this, we provide a comprehensive and current snapshot of existing thinking on test flakiness, covering both academic views and industrial practices, and identify limitations and opportunities for future research.
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    Unique rumen micromorphology and microbiota-metabolite interactions: features and strategies for Tibetan sheep adaptation to the plateau.
    (Frontiers Media S.A., 2024-10-09) Chen Q; Sha Y; Liu X; He Y; Chen X; Yang W; Gao M; Huang W; Wang J; He J; Wang L; Zhang L
    The rumen microbiota-a symbiont to its host and consists of critical functional substances-plays a vital role in the animal body and represents a new perspective in the study of adaptive evolution in animals. This study used Slide Viewer slicing analysis system, gas chromatography, RT-qPCR and other technologies, as well as 16S and metabolomics determination methods, to measure and analyze the microstructure of rumen epithelium, rumen fermentation parameters, rumen transport genes, rumen microbiota and metabolites in Tibetan sheep and Hu sheep. The results indicate that the rumen nipple height and cuticle thickness of Tibetan sheep are significantly greater than those of Hu sheep (p < 0.01) and that the digestion and absorption of forage are greater. The levels of carbohydrate metabolism, lipid metabolism, and protein turnover were increased in Tibetan sheep, which enabled them to ferment efficiently, utilize forage, and absorb metabolic volatile fatty acids (VFAs). Tibetan sheep rumen metabolites are related to immune function and energy metabolism, which regulate rumen growth and development and gastrointestinal homeostasis. Thus, compared with Hu sheep, Tibetan sheep have more rumen papilla and cuticle corneum, and the synergistic effect of the microbiota and its metabolites is a characteristic and strategy for adapting to high-altitude environments.