Browsing by Author "Ventura M"

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    Editors' Prelude to Microbiome Research Reports.
    (OAE Publishing, 2021-07-20) Ventura M; van Sinderen D; Turroni F; Milani C; Munoz J; Haller D; Ross RP; Collado MC; Allen-Vercoe E; Del Rio D; Altermann E; Katayama T; Zoetendal EG; Belzer C; Mena P; Im S-H; Gueimonde M; Margolles A; Ruiz L; Lacroix C; Stanton C; Barbara G; Saminen S; Scott KP; Barrangou R; Bottacini F; Marco ML
    It is our sincere pleasure to introduce a new scientific journal named Microbiome Research Reports (acronym MRR), born out of an ambitious initiative from the Editorial Board of this new journal. Our motivation to initiate a new journal on microbiome research was driven by the importance and impact of the microbiome for human and planetary health, with related research interest and effort driven by the scientific community on the subject. In fact, research findings on this subject represent a Copernican Revolution influencing all research branches of the Life Sciences. For example, vast efforts are currently invested in elucidating potential links between microbiome and disease, which could lead to the discovery of microbial biomarkers for novel therapeutic and preventative strategies. We feel that it is very timely to launch a new journal focusing on Microbiome studies in humans and other animals, i.e., both wild- and domesticated- animals, being convinced that it will be a platform for the dissemination of microbiome discoveries.
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    The evolution of bacterial genome assemblies - where do we need to go next?
    (OAE Publishing Inc., 2022-04-12) Altermann E; Tegetmeyer HE; Chanyi RM; Ventura M
    Genome sequencing has fundamentally changed our ability to decipher and understand the genetic blueprint of life and how it changes over time in response to environmental and evolutionary pressures. The pace of sequencing is still increasing in response to advances in technologies, paving the way from sequenced genes to genomes to metagenomes to metagenome-assembled genomes (MAGs). Our ability to interrogate increasingly complex microbial communities through metagenomes and MAGs is opening up a tantalizing future where we may be able to delve deeper into the mechanisms and genetic responses emerging over time. In the near future, we will be able to detect MAG assembly variations within strains originating from diverging sub-populations, and one of the emerging challenges will be to capture these variations in a biologically relevant way. Here, we present a brief overview of sequencing technologies and the current state of metagenome assemblies to suggest the need to develop new data formats that can capture the genetic variations within strains and communities, which previously remained invisible due to sequencing technology limitations.