Browsing by Author "Li Q"

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    Author Correction: Dense sampling of bird diversity increases power of comparative genomics.
    (2021-04) Feng S; Stiller J; Deng Y; Armstrong J; Fang Q; Reeve AH; Xie D; Chen G; Guo C; Faircloth BC; Petersen B; Wang Z; Zhou Q; Diekhans M; Chen W; Andreu-Sánchez S; Margaryan A; Howard JT; Parent C; Pacheco G; Sinding M-HS; Puetz L; Cavill E; Ribeiro ÂM; Eckhart L; Fjeldså J; Hosner PA; Brumfield RT; Christidis L; Bertelsen MF; Sicheritz-Ponten T; Tietze DT; Robertson BC; Song G; Borgia G; Claramunt S; Lovette IJ; Cowen SJ; Njoroge P; Dumbacher JP; Ryder OA; Fuchs J; Bunce M; Burt DW; Cracraft J; Meng G; Hackett SJ; Ryan PG; Jønsson KA; Jamieson IG; da Fonseca RR; Braun EL; Houde P; Mirarab S; Suh A; Hansson B; Ponnikas S; Sigeman H; Stervander M; Frandsen PB; van der Zwan H; van der Sluis R; Visser C; Balakrishnan CN; Clark AG; Fitzpatrick JW; Bowman R; Chen N; Cloutier A; Sackton TB; Edwards SV; Foote DJ; Shakya SB; Sheldon FH; Vignal A; Soares AER; Shapiro B; González-Solís J; Ferrer-Obiol J; Rozas J; Riutort M; Tigano A; Friesen V; Dalén L; Urrutia AO; Székely T; Liu Y; Campana MG; Corvelo A; Fleischer RC; Rutherford KM; Gemmell NJ; Dussex N; Mouritsen H; Thiele N; Delmore K; Liedvogel M; Franke A; Hoeppner MP; Krone O; Fudickar AM; Milá B; Ketterson ED; Fidler AE; Friis G; Parody-Merino ÁM; Battley PF; Cox MP; Lima NCB; Prosdocimi F; Parchman TL; Schlinger BA; Loiselle BA; Blake JG; Lim HC; Day LB; Fuxjager MJ; Baldwin MW; Braun MJ; Wirthlin M; Dikow RB; Ryder TB; Camenisch G; Keller LF; DaCosta JM; Hauber ME; Louder MIM; Witt CC; McGuire JA; Mudge J; Megna LC; Carling MD; Wang B; Taylor SA; Del-Rio G; Aleixo A; Vasconcelos ATR; Mello CV; Weir JT; Haussler D; Li Q; Yang H; Wang J; Lei F; Rahbek C; Gilbert MTP; Graves GR; Jarvis ED; Paten B; Zhang G
    In Supplementary Table 1 of this Article, 23 samples (B10K-DU-029-32, B10K-DU-029-33, B10K-DU-029-36 to B10K-DU-029-44, B10K-DU- 029-46, B10K-DU-029-47, B10K-DU-029-49 to B10K-DU-029-53, B10K-DU- 029-75 to B10K-DU-029-77, B10K-DU-029-80, and B10K-DU-030-03; styled in boldface in the revised table) were assigned to the incorrect institution. Supplementary Table 1 has been amended to reflect the correct source institution for these samples, and associated data (tissue, museum ID/source specimen ID, site, state/province, latitude, longitude, date collected and sex) have been updated accordingly. The original table is provided as Supplementary Information to this Amendment, and the original Article has been corrected online.
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    Decanoyl-Arg-Val-Lys-Arg-Chloromethylketone: An Antiviral Compound That Acts against Flaviviruses through the Inhibition of Furin-Mediated prM Cleavage
    (MDPI (Basel, Switzerland), 2019-11) Imran M; Saleemi MK; Chen Z; Wang X; Zhou D; Li Y; Zhao Z; Zheng B; Li Q; Cao S; Ye J
    Flaviviruses, such as Zika virus (ZIKV), Japanese encephalitis virus (JEV), Dengue virus (DENV), and West Nile virus (WNV), are important arthropod-borne pathogens that present an immense global health problem. Their unpredictable disease severity, unusual clinical features, and severe neurological manifestations underscore an urgent need for antiviral interventions. Furin, a host proprotein convertase, is a key contender in processing flavivirus prM protein to M protein, turning the inert virus to an infectious particle. For this reason, the current study was planned to evaluate the antiviral activity of decanoyl-Arg-Val-Lys-Arg-chloromethylketone, a specific furin inhibitor, against flaviviruses, including ZIKV and JEV. Analysis of viral proteins revealed a significant increase in the prM/E index of ZIKV or JEV in dec-RVKR-cmk-treated Vero cells compared to DMSO-treated control cells, indicating dec-RVKR-cmk inhibits prM cleavage. Plaque assay, qRT-PCR, and immunofluorescence assay revealed a strong antiviral activity of dec-RVKR-cmk against ZIKV and JEV in terms of the reduction in virus progeny titer and in viral RNA and protein production in both mammalian cells and mosquito cells. Time-of-drug addition assay revealed that the maximum reduction of virus titer was observed in post-infection treatment. Furthermore, our results showed that dec-RVKR-cmk exerts its inhibitory action on the virus release and next round infectivity but not on viral RNA replication. Taken together, our study highlights an interesting antiviral activity of dec-RVKR-cmk against flaviviruses.
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    The Effects of Institutional Difference and Resource Seeking Intent on Location Choice of Chinese Outward FDI
    (Scientific Research Publishing Inc, 13/04/2018) Kang Y; Li Q
    This study seeks to explain how differences in political risk and economic freedom between host and home countries interact with investing firms’ resource-seeking intent to influence the firms’ outward foreign direct investment (FDI) location choice. Using panel data covering Chinese outward FDI in 62 host countries during the period of 2003-2014, we performed panel data regression analysis. The results show that when firms’ resource seeking intention is high, the FDI location choice is negatively associated with the differences in political risk, but positively associated with the differences in economic freedom between China and the host countries. The results also show that there is a substituting effect between political risk and economic freedom in their interactions with resource-seeking intent to influence FDI location choice. The findings suggest that the Chinese firms’ outward FDI location choice is a result of the interplay and the fit between the firms’ external legitimacy in the host countries and the firms’ internal legitimacy within the multinational organization.